The Railroaders Memorial Museum seeks to preserve the stories and contributions of Central Pennsylvanians who left an imprint on their communities, industry, and nation. Museum displays include a rich array of artifacts, immersive environments, and life size dioramas of railroad workers performing various tasks typical of the Altoona Shops. Various orientation films present colorful context of the people and lifestyles that composed the city's railroading community. A well-stocked gift shop and digital database serves as additional amenities for the visiting public.

First opened in 1980, the museum relocated in 1998 to the Pennsylvania Railroad's former Master Mechanic's Building. Constructed in 1882, the structure was used for a century of railroad operations. Initially, the railroad's physical and chemical laboratories were housed here. In subsequent years, the building was used for medical offices, storage, and railroad police headquarters—which included an indoor firearms range in the basement. The Master Mechanic's Building is the sole survivor of Altoona's Machine Shops. The site stands as a stunning example of railroad architecture and a monument to the individuals who built it.

When the Railroaders Memorial Museum opened the Master Mechanics Building, it became apparent that a facility was needed to care for the Museum's growing collection of rolling stock. The Museum embarked on the design of a quarter-roundhouse to provide a place for restoration, maintenance, and secure exhibition. The first pie-shaped wedge of the building was completed in summer 2002. Additional funding was secured in 2007 and 2010 to complete the building and house the Museum's most prized possession, Pennsylvania Railroad K-4 Locomotive 1361.
 

The facility was funded by Robert Bennett, a generous Museum patron from Los Angeles, as a tribute to his grandfather, William Henry "Harry" Bennett. Harry served as the first foreman of the newly constructed Juniata Locomotive Shops in 1889. Promoted to master mechanic in 1901, he oversaw the construction of K-4 1361 as well as over 6,000 other locomotives and the construction of the East Altoona Roundhouse. Harry Bennett held the position of master mechanic until 1921, longer than anyone else had. The Harry Bennett Memorial Roundhouse features a working 105-foot turntable, indoor storage bays, and outdoor storage spurs to display and interpret the Museum's rolling stock collection.